I now have MySQLdb working on Mac OS 10.7.5 with Python 2.7, MySQL 5.6 and MySQLdb 1.2.4b4.

Thanks a ton!

server:MySQL-python-1.2.3 User$ sudo python setup.py buid
Password:
Traceback (most recent call last):
File “setup.py”, line 5, in
from setuptools import setup, Extension
ImportError: No module named setuptools

OSx version: 10.7.4

Abc-MacBook:~ Abc$ file $(which python)
/usr/bin/python: Mach-O universal binary with 2 architectures
/usr/bin/python (for architecture x86_64): Mach-O 64-bit executable x86_64
/usr/bin/python (for architecture i386): Mach-O executable i386

Abc-MacBook:~ Abc$ file /usr/local/mysql/bin/mysql
/usr/local/mysql/bin/mysql: Mach-O 64-bit executable x86_64

Abc-MacBook:~ Abc$ /usr/local/mysql/bin/mysql_config –cflags
-I/usr/local/mysql/include -Os -g -fno-common -fno-strict-aliasing -arch x86_64

Abc-MacBook:~ Abc$ more .profile

# MacPorts Installer addition on 2012-07-08_at_11:53:29: adding an appropriate PATH variable for use with MacPorts.
# export PATH=/opt/local/bin:/opt/local/sbin:$PATH
PATH=”/usr/local/mysql/bin:${PATH}”
export PATH
export DYLD_LIBRARY_PATH=/usr/local/mysql-5.5.25a-osx10.6-x86_64/lib/:$DYLD_LIBRARY_PATH
export VERSIONER_PYTHON_PREFER_64_BIT=yes
export VERSIONER_PYTHON_PREFER_32_BIT=no
# Finished adapting your PATH environment variable for use with MacPorts.
alias mysql=/usr/local/mysql/bin/mysql
alias mysqladmin=/usr/local/mysql/bin/mysqladmin

Error:

Abc-MacBook:MySQL-python-1.2.3 Abc$ python
Python 2.7.1 (r271:86832, Jul 31 2011, 19:30:53)
[GCC 4.2.1 (Based on Apple Inc. build 5658) (LLVM build 2335.15.00)] on darwin
Type “help”, “copyright”, “credits” or “license” for more information.
>>> import MySQLdb
/Library/Python/2.7/site-packages/MySQL_python-1.2.3-py2.7-macosx-10.7-intel.egg/_mysql.py:3: UserWarning: Module _mysql was already imported from /Library/Python/2.7/site-packages/MySQL_python-1.2.3-py2.7-
macosx-10.7-intel.egg/_mysql.pyc, but /Users/Abc/Downloads/MySQL-python-1.2.3 is being added to sys.path
Traceback (most recent call last):
File “”, line 1, in
File “MySQLdb/__init__.py”, line 19, in
import _mysql
File “build/bdist.macosx-10.7-intel/egg/_mysql.py”, line 7, in
File “build/bdist.macosx-10.7-intel/egg/_mysql.py”, line 6, in __bootstrap__
ImportError: dlopen(/Users/Abc/.python-eggs/MySQL_python-1.2.3-py2.7-macosx-10.7-intel.egg-tmp/_mysql.so, 2): no suitable image found. Did find:
/Users/Abc/.python-eggs/MySQL_python-1.2.3-py2.7-macosx-10.7-intel.egg-tmp/_mysql.so: mach-o, but wrong architecture

Waiting for your responses. Thanks!!!